Same as I did for Fallout New Vegas I made a loader (well actually updated the FNV one) to load Skyrim with the Large Address Aware Flag.
Details on Skyrim Nexus
Dec 132011
Oct 262010
4GB Fallout New Vegas is a loader for Fallout New Vegas that sets the Large Address Aware bit on the executable but not causing steam to detect a modified executable. It also provide some small stutter improvements.